thre are several members around that use HPTuners software. the best person to ask any questions to would be foff667. bill is a great tuner and works as a beta tester for HPTuners.
there are a ton of help menu's in the software, a bunch more on their site, and even a tune library on their web site that is available to all customers. the software is very well layed out and easy to use, you won't have any problem getting started.
good luck with it